Angela Thyer standing beside the water

Physician. Behavioral Scientist.
Clinical AI Strategist.

Designing healthcare
for the age of AI.

I work with health systems, employers, technology companies, and physicians on a practical question: which parts of care can we safely entrust to AI? Together, we design the care model and work out how to test it.

The problem I’m interested in

Healthcare doesn’t just need better AI.
It needs a new model of care.

Helping a physician get through the day faster is useful. But it leaves the same physician responsible for an ever-growing number of patients. Staffing shortages, long waits, and rising costs call for a closer look at how care is organized.

I’m interested in where AI can take on defined clinical tasks, with evidence that it works and a clear route back to a person when it doesn’t. That would give clinicians more room for the decisions and relationships that need them.

  • Better access
  • Lower costs
  • Healthier people
  • A more sustainable
    healthcare system

The Autonomy Continuum

Who acts. Who reviews. Who is responsible.

  1. 01

    Assist

    AI gathers information, summarizes, and supports clinicians.

  2. 02

    Recommend

    AI proposes clinical actions; clinicians approve.

  3. 03

    Act + Review

    AI executes bounded actions; clinicians review retrospectively.

  4. 04

    Supervised Autonomy

    AI operates within a defined scope; humans audit and manage exceptions.

  5. 05

    Bounded Autonomy

    AI independently manages validated workflows with defined escalation, surveillance, and accountability.

Progression depends on evidence, safeguards, monitoring, and clear accountability.

“The question isn’t whether AI can replace doctors. It’s which clinical decisions still require a doctor—and what evidence should be required before responsibility can safely move to AI.”

What I Do

01

AI Care Model Design

I help teams decide which parts of care AI can take on, which decisions need a clinician, and when the system should ask for help.

What this involves

The work can include mapping a patient’s care journey, assigning responsibility at each step, and setting clear rules for escalation.

02

Clinical AI Testing & Validation

A model can perform well on a test and still fail in practice. I help teams design pilots that examine what happens to patients, clinicians, and the cost of care.

What this involves

What gets missed? When do clinicians override the system? Who benefits, who is left out, and does the care actually improve? These questions belong in the evaluation from the start.

03

Behavioral Adoption & Trust

Will clinicians use the system? Will patients follow its advice? I bring behavioral science to the practical problem of knowing when to rely on AI and when to question it.

What this involves

This means examining resistance, over-reliance, and the small decisions in a workflow or interface that change how people behave.

When to bring me in

Explore an illustrative home-monitoring workflow →

An illustrative workflow · not a client case study

Blood pressure at home.
Who takes the next step?

A connected cuff can send a reading. The harder work is deciding what happens next: what the patient hears, what the team sees, and who follows through. Explore one possible model below.

Fictional readings and scripted responses. This is a design example, not a working monitoring service or medical advice. No health data is collected here.

Choose a situation

Routine check-in: Continue the agreed plan

At home

Example patient view

Blood pressure mmHg

128 / 78

Second reading: 126 / 78

Two readings received · no symptoms reported

AI coach · example response

Your readings have been saved. Your next check-in is scheduled in your care plan.

The cuff measures. The widget displays. The care plan sets the boundaries.

01 / The next action

Continue the agreed plan

In this fictional case, the readings meet the care team’s agreed monitoring rules. The system records them and adds them to the next summary.

02 / Back to the clinical team

Show the evidence, not just an alert.

Trend summary with both source readings, measurement times, reported symptoms, and any missing information. No extra alert for this check-in.

03 / Responsibility

Monitoring service

The assigned team reviews summaries on the schedule agreed before enrollment.

How would we collect the data?
  1. Agree the care plan. Confirm consent, patient identity, eligibility, an appropriate validated upper-arm cuff and cuff size, measurement training, and a named clinical team. Offer a supported alternative for people who cannot use the app.
  2. Capture the reading and its context. A connected cuff could send results through a phone or cellular connection. Record both values in mmHg, measurement time and time zone, device/source, receipt time, quality flags, and patient-reported symptoms. Preserve paired readings rather than only an average.
  3. Check before interpreting. Identify duplicate, delayed, missing, or mismatched records. Label manual entries and uncertain measurements. Keep patient reports separate from device measurements and AI inferences.
  4. Make the record traceable. Send authorized data into the clinical record or an agreed review queue. Retain the source reading, rule and model version, message sent, delivery status, clinician acknowledgment, and final disposition. Define access controls and retention before the pilot.

Measurement foundation: American Heart Association guidance on home monitoring. The collection and routing design above is illustrative.

What is the AI allowed to do?

Inside the agreed scope

Record readings, check completeness, provide approved measurement reminders, summarize trends, and route cases using clinician-approved rules. Any generated summary must be checked against the source data.

Back to a person

Diagnosis, medication changes, conflicting information, unresolved measurement problems, and cases outside the agreed population or protocol. The AI cannot rewrite its own escalation rules or expand its authority.

Before enrollment, specify eligibility and exclusions, response times, urgent instructions, out-of-hours cover, technical downtime procedures, and who owns each unresolved case. Assess the actual software functions and regulatory requirements before clinical use; this illustration is not a validated or cleared product.

What can we borrow from autopilot and self-driving cars?

Define the conditions in which autonomy is allowed.

The useful parallel is the operating boundary: which task, for which patient, with what data, and under whose supervision? A home-monitoring system should recognize when it has left those conditions and hand responsibility to a person.

The comparison has limits. Clinical care has different hazards and response times. A clinical inbox is not an immediate takeover mechanism. A safe handoff requires a named recipient, acknowledgment, a deadline, and a backup. Evidence from driving or aviation does not establish safety in healthcare.

The test is the whole care pathway

Can this make care
cheaper and more reliable?

That is a question to test, not a benefit to assume. Compare with current care over a defined period, using the same outcome definitions and an appropriate study design.

Does it catch what matters?
Missed and unnecessary escalations, time to acknowledgment and action, unresolved cases, and clinical outcomes. Review cases independently of the AI’s own judgments.
Does it work for the people using it?
Patient effort, usable readings, follow-up completion, clinician overrides, and results across language, disability, connectivity, and other relevant groups.
What does the full pathway cost?
Devices, software, integration, coaching, staff review, outreach, training, and downstream care. Count additional alerts and work as well as time saved. Payment and savings are different questions.

Before expanding: test with synthetic failure cases; evaluate in shadow mode without changing care; then run a limited, supervised pilot with predefined success measures and stop rules. Reassess after material model or workflow changes.

The Future of Care

Conversations about
healthcare after AI.

I’m developing a series of conversations with people who see healthcare from different angles: clinicians, technologists, employers, payers, and colleagues in behavioral science, policy, cybersecurity, and finance. I want to put difficult questions on the table before the answers are treated as settled.

Join the Conversation

On the agenda

Which of our clinical workflows could AI manage safely—and which need a human in the loop?

How do we test AI-enabled clinical workflows?

Can AI make healthcare cheaper—and care more reliable?

Conversations coming soon.

Questions I’m Working On

  1. 01

    When is an AI system ready to make a clinical decision without prospective physician review?

  2. 02

    How should continuously evolving AI systems be clinically validated?

  3. 03

    Who should be responsible when an autonomous clinical system makes an error?

  4. 04

    How do we create appropriate—not maximal—trust in clinical AI?

  5. 05

    Can AI lower healthcare spending rather than simply increase healthcare productivity?

  6. 06

    How should healthcare organizations protect autonomous agents from manipulation and cyberattack?

  7. 07

    Which clinical workflows should become autonomous first?

About Angela

Twenty years in medicine.
Still asking how care could work better.

Angela Thyer, MD, MSc
Physician · 20+ years of clinical experience

After more than two decades practicing medicine, I became increasingly interested in a problem medicine alone couldn’t solve: knowing what patients should do is very different from helping people actually do it.

That led me to behavioral science. AI now raises a second question: if machines can increasingly perform parts of clinical reasoning and care delivery, how should healthcare be redesigned around that capability?

These are the questions I now work on with organizations planning how to use AI in care.

Venture Mentorship Program (VMP)Involvement at Johns HopkinsMSc, Behavioral Science London School of Economics

Let’s Talk

What are you
working on?

If you’re working through a care model, planning an AI pilot, or have a question you’d like to discuss, I’d like to hear from you.

Start a Conversation